Pain in your joints isn’t something you want to deal with — but sometimes it’s inevitable. Whether you’re active in sports or your joints have taken a lot of abuse over the years, the protective tissues can wear away, leading to pain and decreased mobility. Regenerative medicine is a treatment that can help, especially with A2M therapy.
At Commonwealth Musculoskeletal Medicine, our team is well-versed in problems affecting your joints. Dr. Mark Conliffe is our in-house specialist, treating neuromusculoskeletal issues that affect your life. Dr. Conliffe and his team offer many different treatments to get rid of your pain.
A2M therapy stands for alpha 2 macroglobulin, which is a molecule that your body makes naturally. A2M therapy is a type of regenerative medicine used to stop cartilage degeneration in your joints and relieve symptoms associated with arthritis.
Alpha 2 macroglobulin is made in your liver and is what’s considered a protease inhibitor. It’s categorized as a plasma protein and is free-flowing in your blood. Although this molecule has many jobs, one of its main jobs is to deactivate proteases in your body that damage cartilage within your joints.
A2M also has strong anti-inflammatory properties, making it ideal for regenerative medicine and arthritis treatment. However, the molecules of A2M are actually too large to get into the affected joint themselves, which is why it’s given as an injection.
For this treatment, you’ll need to have your blood drawn. Afterward, the A2M molecules are separated and condensed into a single injection. Once the preparation is ready, Dr. Conliffe cleans off the area of pain and injects the A2M directly into the affected joint.
Typically, A2M therapy is used for osteoarthritis in your joints. This condition can affect any joint in your body, especially your knees, hips, and spine.
Osteoarthritis is a degenerative form of arthritis that causes the breakdown of cartilage within your joints. The cartilage acts as a protective barrier between the bones in your joint. It reduces friction and prevents damage to the bone and other tissues.
However, with osteoarthritis, the cartilage wears away, causing both pain and chronic inflammation in the affected joint. If left untreated, osteoarthritis may end up damaging the joint so severely that you need joint replacement surgery.
A2M is an innovative therapy that’s used to prevent the premature breakdown of the cartilage in your joints. By doing so, it also decreases inflammation and pain in the affected area.
Although A2M therapy and platelet-rich plasma therapy both work to reduce pain in your joint, they both work a little differently. While one is fighting off cartilage loss, the other is regenerating new tissues through your body’s natural healing process.
Both of these injections require a blood draw to get access to your body’s molecules and cells. With A2M, it’s the alpha 2 macroglobulin molecule being extracted. PRP requires the platelets and plasma to be separated from the rest of your blood products.
A2M therapy works to stop the progression of arthritis by attaching to harmful enzymes in your body that attack the cartilage in your joints. By binding to these enzymes, A2M can fight off the destruction first-hand, saving your cartilage and chondrocytes that protect your joint.
PRP, on the other hand, uses platelets and plasma to regenerate certain tissues in your joint. Platelets not only help with clotting, they also carry essential growth proteins that aid with injury. In the case of osteoarthritis in your joint, the injury is to the cartilage and protective tissues.
Both injections are extremely helpful, especially when it comes to osteoarthritis in your joints. A2M works with your body to fend off harmful processes that can lead to joint breakdown and inflammation.
To find out if A2M therapy can help you fight off pain, don’t hesitate to call our office today at 502-771-1012, or book an appointment online with Dr. Conliffe on our website.